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The dosage of antihyperglycemic therapy with Sitagliptin Phosphate+Metformin should be individualized on the basis of the patient's current regimen, effectiveness and tolerability while not exceeding the maximum recommended daily dose of 100mg sitagliptin.
Generic Medicine Info. Indications and Dosage. Oral. Type 2 diabetes mellitus. Adult: As an adjunct to diet and exercise to improve glycaemic control: Monotherapy or in combination with other antidiabetic agents: 100 mg once daily. Renal Impairment.
Indications and Dosage. Oral. Type 2 diabetes mellitus. Adult: Each tab contains sitagliptin and metformin (conventional: 50 mg/500 mg, 50 mg/1000 mg; extended-release: 50 mg/500 mg, 50 mg/1000 mg, 100 mg/1000 mg): Patients not currently treated w/ metformin: Initially, 100 mg/1000 mg daily.
Sitagliptin/Metformin tablets combine two medications: Sitagliptin, a DPP-4 Inhibitor, and Metformin, a Biguanide. They work together to manage blood sugar levels in adults with type 2 diabetes by increasing insulin production after meals and reducing the body's sugar production.
Individualized dosing. Initial therapy: Starting dose 50 mg/500 mg bid. May be titrated up to 50 mg/1 g bid. Patient inadequately controlled on metformin monotherapy Sitagliptin 50 mg bid + metformin already taken. Patient inadequately controlled on sitagliptin monotherapy 50 mg/500 mg tab bid. May be titrated up to 50 mg/1 g tab bid.
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