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Compare Divalproex Sodium vs Valproic Acid head-to-head with other drugs for uses, ratings, cost, side effects and interactions.
May 14, 2021 · Valproic acid (VPA) is an organic weak acid, while its conjugate base is called valproate. The sodium salt of the acid is called sodium valproate and a coordination complex of the two is known as divalproex sodium (DVP). Pharmacokinetically, VPA is very similar, but not the same as DVP.
Conclusion: Given these results and that valproic acid is much less expensive than divalproex sodium, valproic acid appears to be a satisfactory substitution for divalproex sodium in the treatment of frequently hospitalized psychotic patients.
Feb 25, 2022 · Depakene vs Depakote: What’s the Difference? Depakene (valproic acid) and Depakote (divalproex sodium) are two very similar medications used to treat seizures. When talking about them together, healthcare professionals call these medications valproate products. You shouldn’t switch between Depakene and Depakote without a healthcare provider’s OK.
Objective: The authors examined clinical differences between divalproex sodium and generic immediate-release valproic acid. Method: This 6-year prospective, quasi-experimental clinical trial compared the effectiveness and tolerability of divalproex and valproic acid.
May 1, 2000 · CONCLUSION: Given these results and that valproic acid is much less expensive than divalproex sodium, valproic acid appears to be a satisfactory substitution for divalproex sodium in the...
Mar 19, 2024 · Divalproex sodium is the stable, coordinated compound of sodium valproate and VPA. Due to its distinctive extensive spectrum of anticonvulsant effects, divalproex sodium is used to manage a wide range of seizure disorders, such as myoclonic epilepsy syndromes, absence epilepsy, generalized convulsions, partial seizures, and status ...
CONCLUSION: Given these results and that valproic acid is much less expensive than divalproex sodium, valproic acid appears to be a satisfactory substitution for divalproex sodium in the treatment of frequently hospitalized psychotic patients.
Compare Valproate Sodium vs Valproic Acid head-to-head with other drugs for uses, ratings, cost, side effects and interactions.
Results: Patients treated with divalproex sodium compared with patients treated with valproic acid were less likely to have gastrointestinal side effects (14.7% vs. 28.7%, p = .003), specifically anorexia (6.0% vs. 14.7%, p = .012), nausea or vomiting (6.7% vs. 16.7%, p = .007), and dyspepsia (11.3% vs. 22.0%, p = .013).
