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  1. Aug 14, 2023 · The monospot test is a latex agglutination test which utilizes equine erythrocytes as the primary substrate and tests for specific heterophile antibodies produced by the human immune system in response to EBV infection.

  2. Dec 16, 2020 · A mononucleosis spot (or Monospot) test is a blood test used to determine whether you have contracted the Epstein-Barr virus, the virus that causes infectious mononucleosis.

  3. The mononuclear spot test or monospot test, a form of the heterophile antibody test, is a rapid test for infectious mononucleosis due to Epstein–Barr virus (EBV). It is an improvement on the Paul–Bunnell test. The test is specific for heterophile antibodies produced by the human immune system in response to EBV

  4. Nov 16, 2021 · The Monospot test detects heterophile antibodies produced by the immune system in response to Epstein-Barr virus (EBV) infection. These antibodies can cross-react with other types of cells, including horse red blood cells (the ones used in the monospot).

  5. Types of mono tests include: Monospot test. This test looks for specific antibodies in the blood. These antibodies show up during or after certain infections, including mono. EBV antibody test. This test looks for EBV antibodies, the main cause of mono. There are different types of EBV antibodies.

  6. The monospot test, also known as the Paul-Bunnell test, is a form of the heterophile antibody test used to rapidly screen infectious mononucleosis (mono). Epstein–Barr virus (EBV) causes the disease infectious mononucleosis.

  7. Mono tests are used to help diagnose a mono infection. Your provider may use a monospot to get fast results. Results are usually ready within an hour. But this test has a high rate of false negatives. So monospot tests are often ordered with an EVB antibody test and other tests that look for infections. These include:

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