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  1. link.springer.com › referenceworkentry › 10Extracellular Matrix Remodeling on Cancer Progression

    2 hours ago · There are various macromolecules that make up the extracellular matrix (ECM). It is composed of proteoglycans, polysaccharides, glycoproteins, and fibrous proteins, which give the ECM its dynamic shape. In terms of tissue development and homeostasis, the ECM plays a major role. In addition, it serves as one of the major structural components of ...