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Abstract. As our knowledge on the natural history of chronic obstructive pulmonary disease (COPD) progresses, a conceptual model simply based on an accelerated decline of lung function in adult life in response to smoking has become inadequate to capture the complexity of this disease, and increasing attention is being given to possible ...
Apr 18, 2019 · To BE or not to BE, that is the question. Nature Biotechnology 37 , 520–522 ( 2019) Cite this article. In vivo studies indicate that cytosine but not adenine base editors induce elevated levels ...
3 CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China. liyang@picb.ac.cn. PMID: 31000812. DOI: 10.1038/s41587-019-0119-x. To BE or not to BE, that is the question.
Sep 16, 2011 · Let us carry some proverbial owls to Athens or coals to Newcastle, that is, revisit issues that have been discussed and examined by so many different voices in the past and the present. However, those issues by themselves are so powerful and important, so urgent and difficult that we must never tire of examining them always anew because they pertain centrally to our own human existence and ...
Oct 19, 2023 · Hamlet’s desperate question, "To be, or not to be," occurs in Act 3, Scene 1, and is the most famous and celebrated because of its philosophical nature, questioning life and death–in short, existence. Hamlet's dilemma is whether it is worth it to exist, and he weighs life's worth against the nothingness of nonexistence as he toys with the ...
Jul 12, 2020 · The focus of our study is therefore aconitase, from its first localization inside the glyoxysomes to its relocation. We also examine data concerning the role of the enzyme malate dehydrogenase in the glyoxylate cycle and data of the expression of aconitase genes in Arabidopsis and other selected higher plants. We then propose a new model ...
Jun 1, 2004 · This article attempts to answer that question through an analysis of (a) the history of categorical eligibility for special education (b) its purpose and (c) its problems.
