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Sep 8, 2020 · Essential features. Most patients are asymptomatic or have mild self limited dyspeptic symptoms but some present with abdominal pain with or without peptic ulcer disease. H. pylori organisms are Gram negative, helical or spiral shaped and flagellate.
H. pylori in vivo and under optimum in vitro conditions is an S-shaped bacterium with 1 to 3 turns, 0.5 ×5 μm in length, with a tuft of 5 to 7 polar sheathed flagella ( 40, 51 ). This morphology has been correlated with maximum in vitro motility ( 106 ).
Nov 21, 2014 · Abstract. Helicobacter pylori is a helical-shaped, gram negative bacterium that colonizes the human gastric niche of half of the human population 1,2. H. pylori is the primary cause of gastric cancer, the second leading cause of cancer-related deaths worldwide 3.
Observation: When viewed under the microscope, H. pylori may appear to be rod or spiral shaped. Since the bacteria does not retain the primary stain (a characteristic of gram negative bacteria) they will appear reddish/purple in color (color of the counter stain).
Download scientific diagram | Microscopical images of Gram-stained H. pylori under light microscopy showing the different stages in morphologic conversion. Pure spiral forms at 24 h...
Table 1. Virulence factors identified in H. pylori. Flagella and motility. The curved morphology of H. pylori and the polar motility caused by flagella in one end cause screw-like movements, which may enable the organism to penetrate the mucin layer.
Endoscopic biopsy involves obtaining tissue from the stomach using a thin flexible tube introduced through the mouth and testing for the presence of H pylori under the microscope. It is currently the most accurate available test, however it causes physical discomfort to the patient, with associated risks for harm.
