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  1. Dictionary
    Down syn·drome
    /ˈdoun ˌsindrōm/

    noun

    • 1. a congenital condition characterized by a distinctive pattern of physical characteristics including a flattened skull, pronounced folds of skin in the inner corners of the eyes, large tongue, and short stature, and by some degree of limitation of intellectual ability and social and practical skills. It usually arises from a defect involving chromosome 21, usually an extra copy (trisomy-21).

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  2. www.mayoclinic.org › diseases-conditions › down-Down syndrome - Symptoms and causes - Mayo Clinic

    Mar 8, 2018 · Down syndrome is a genetic disorder caused by an extra copy of chromosome 21. It affects intellectual and physical development, and can cause health problems such as heart defects. Learn more about the types, risk factors and diagnosis of Down syndrome.

  3. en.wikipedia.org › wiki › Down_syndromeDown syndrome - Wikipedia

    Down syndrome or Down's syndrome, also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. It is usually associated with developmental delays, mild to moderate intellectual disability, and characteristic physical features.

  4. www.cdc.gov › birth-defects › aboutDown Syndrome | Birth Defects | CDC

    May 16, 2024 · Down syndrome is a genetic condition where a person has an extra copy of chromosome 21. It can affect how their brain and body develop and cause physical and mental challenges. Learn about the types, risk factors, screening and diagnosis, and resources for people with Down syndrome.

  5. www.healthline.com › health › down-syndromeDown Syndrome: Causes, Types, and Symptoms - Healthline

    Nov 28, 2023 · Down syndrome is a genetic condition caused by an extra copy of chromosome 21. It can affect physical and mental development and lead to various health complications. Learn about the types, symptoms, screening, and treatment of Down syndrome.

  6. my.clevelandclinic.org › health › diseasesDown Syndrome: Symptoms & Causes - Cleveland Clinic

    Jan 31, 2023 · Down syndrome is a genetic condition where a person has an extra copy of chromosome 21. Learn about the physical, cognitive and behavioral symptoms, the types and causes of Down syndrome, and how it's diagnosed before and after birth.

  7. medlineplus.gov › downsyndromeDown Syndrome: MedlinePlus

    Jan 26, 2024 · Summary. What is Down syndrome? Down syndrome is a condition in which a person has an extra chromosome or an extra piece of a chromosome. This extra copy changes how a baby's body and brain develop. It can cause both mental and physical challenges during their lifetime.

  8. www.downsyndrome.org.au › about-down-syndrome › what-is-downWhat is Down syndrome? – Down Syndrome Australia

    Down syndrome is a genetic condition, not an illness or disease. It is nobody’s fault. There is no cure and it does not go away. Find out more in our fact sheet and video. About Down syndrome (Fact sheet) About Down syndrome (Translations) Learn more about Down syndrome. How is Down syndrome diagnosed?