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Jun 25, 2023 · Targeted temperature management improves neurological outcomes and decreases mortality through multiple mechanisms that alter the cascade of deleterious metabolic, cellular, and molecular changes that occur following global ischemia.
Oct 26, 2022 · Options in temperature management comprise targeted hypothermia, usually defined as lowering core body temperature to 32 °C to 36 °C, and targeted normothermia, which aims for a core body temperature of <37.7 °C, with fever prevention in the further course of treatment.
Jul 26, 2019 · Targeted temperature management (TTM), previously known as mild therapeutic hypothermia, in selected patients surviving out-of-hospital sudden cardiac arrest (OHCA) can significantly improve...
Nov 9, 2021 · Recently, the Targeted Temperature Management-2 (TTM2) trial randomized 1,861 patients to targeted hypothermia (33°C) or targeted normothermia (37.8°C) and found no benefit of targeted hypothermia in improving survival at 6 months.
Aug 29, 2022 · Targeted temperature management (TTM) refers to strict temperature control following out-of-hospital cardiac arrest (OHCA). Current evidence is to aim for normothermia and actively treat fevers.
Targeted temperature management (TTM) previously known as therapeutic hypothermia or protective hypothermia is an active treatment that tries to achieve and maintain a specific body temperature in a person for a specific duration of time in an effort to improve health outcomes during recovery after a period of stopped blood flow to ...
Targeted temperature management (TTM) in today's modern era, especially in intensive care units represents a promising multifaceted therapy for a variety of conditions. Though hypothermia is being used since Hippocratic era, the renewed interest of late has been since early 21 st century.
Background Targeted temperature management (TTM) is often used in neurocritical care to minimize secondary neurologic injury and improve outcomes. TTM encompasses therapeutic hypothermia, controlled normothermia, and treatment of fever.
In this review, the term Targeted Temperature Management (TTM) will be used to refer to mild induced therapeutic hypothermia as suggested by the most recent guidelines. Go to: 2. CURRENT GUIDELINES.
Dec 17, 2012 · Targeted temperature management (TTM) has been investigated experimentally and used clinically for over 100 years. The initial rationale for the clinical application of TTM, historically referred to as therapeutic hypothermia, was to decrease the metabolic rate, allowing the injured brain time to heal.
