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DUMBBELLS medical mnemonic – cholinergic overdose. This is an example of a mnemonic that is commonly used in the real world to diagnose cholinergic overdose. D iarrhoea.
Apr 2, 2020 · DUMBBELLS is a mnemonic for the signs and symptoms of a cholinergic crisis, resulting from excess cholinergic activation. Learn how to recognise a Cholinergi...
Dec 13, 2022 · Colloquially denoting "MDs' Bedbug Pound," with pound semantically signaled by the letters "Lb", this mnemonic corresponds to the clinical features of acute cholinergic toxicity, relating to the stimulation of muscarinic receptors and which are consistent with cholinergic excess manifestations that include 1,2: M: miosis.
The symptoms of organophosphate poisoning include over activity of the parasympathetic nervous system (“DUMBBELS” * ); stimulation followed by inhibition of nicotinic receptors at autonomic ganglia and on the skeletal muscle; and stimulation of cholinergic receptors in the CNS.
A cholinergic crisis is an over-stimulation at a neuromuscular junction due to an excess of acetylcholine (ACh), as a result of the inactivity of the AChE enzyme, which normally breaks down acetylcholine.
Dec 5, 2022 · Cholinergic toxicity may result from insecticides, nerve agents, medications, and mushrooms. The most common cause of cholinergic toxicity worldwide is exposure to organophosphate and carbamate insecticides.
Sep 4, 2020 · A cholinergic crisis develops as a result of overstimulation of nicotinic and muscarinic receptors at the neuromuscular junctions. This is usually secondary to the inactivation or inhibition of acetylcholinesterase (AChE), the enzyme responsible for the degradation of acetylcholine (ACh).
