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  1. Aug 14, 2018 · Breakthrough pain is a sudden and brief flare-up of pain from a chronic condition like arthritis or cancer. Even if you’ve been managing your pain with medication,...

  2. Aug 29, 2023 · Breakthrough pain occurs in people living with chronic medical conditions. These individuals typically take medications that manage their baseline pain. However, sometimes pain can still break through current treatment.

  3. Oct 4, 2017 · Breakthrough pain is also known as a flare-up or flare. It tends to occur in waves, peaking quickly then decreasing in intensity. It can last anywhere from minutes to hours. Much of the...

  4. Jan 19, 2007 · Breakthrough pain is severe or excruciating pain of rapid onset that can disable or even immobilize the patient. Patients with BTP should be assessed after baseline persistent pain has been stabilized with around-the-clock (ATC) analgesics.

  5. Jun 13, 2010 · For people in chronic pain, sharp spikes of breakthrough pain can be a big problem. What causes it -- and how can you find pain relief? That's an important question for many patients,...

  6. Breakthrough pain is a transitory flare of pain that occurs on a background of well-controlled baseline pain. Breakthrough pain is highly prevalent among patients with cancer and predicts more severe pain, pain-related distress and functional impairment, and relatively poor quality of life.

  7. Jan 19, 2007 · It is most commonly defined as an abrupt, short-lived, and intense pain that “breaks through” the around-the-clock analgesia that controls persistent pain. The three subtypes of BTP are incident, idiopathic, and end-of-dose failure. BTP also is categorized as somatic, visceral, neuropathic, or mixed.

  8. Breakthrough pain is a sudden onset of pain that "breaks through" the long-acting medication prescribed to treat moderate to severe persistent pain. It is a type of pain that can be experienced by someone who has chronic pain.

  9. Jan 4, 2013 · Breakthrough pain is defined as the transient exacerbation of pain occurring in a patient with otherwise stable, persistent pain. It is estimated to affect over 50% of patients, particularly those with moderate to severe background pain. Breakthrough pain is one of the most difficult pain syndromes to treat.

  10. Breakthrough pain can often be successfully treated by tailoring opioid therapy based on the subtype of BTP. These characteristics of BTP will determine the most appropriate opioid compound (i.e., hydrophilic vs lipophilic) and most effective mode of drug delivery.

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