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  1. Jul 20, 2010 · Inspired by the experiment in the 1990s that saw a mouse grow a "human ear" on its back, Splice tells the familiar story of scientists who create something strange - and slimey - in the lab.

  2. Jun 6, 2024 · Produced by Guillermo del Toro, Splice stars Adrian Brody and Sarah Polley as a young scientist couple who, after introducing human DNA into their work with genetic splicing, create a human-animal hybrid being called Dren, who becomes like the couple's child.

  3. Oct 25, 2010 · The premise is simple: two young, attractive and brilliant geneticists, Elsa and Clive (Sarah Polley and Adrien Brody), cook up a human-animal hybrid named Dren.

  4. Feb 29, 2020 · In Splice, Dren's creation is overseen by two genetic engineers, Clive and Elsa (Polley), who continue on with their forbidden project after it's terminated by their company.

  5. What's so interesting about the story, in spite of what the trailer suggests, is that the creature artificially spawned by genetic engineers Clive and Elsa (Adrian Brody and Sarah Polley) is not an antagonist for the vast majority of the film.

  6. Apr 30, 2024 · In a GQ oral history, director Doug Liman, writer John August, and then-rising stars Timothy Olyphant and Sarah Polley tell us how it really went down. Two words: “Tantra, baby!”

  7. Jun 4, 2010 · Dark, sleek, funny and creepily infectious, the genetic-engineering horror-comedy "Splice" is a dynamic comeback vehicle for Canadian genre director Vincenzo Natali, who made a splash a few years...