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Jul 17, 2024 · Amiodarone (antiarrhythmic): increases bioavailability and effects of benzodiazepines. Monitoring is required to adjust doses. Hypertonic agents (amlodipine, atenolol, lisinopril): risk of respiratory hypotension. Antacids: decrease the absorption time of benzodiazepines. A 2-h delay between the two molecules avoids this interaction.
Jul 17, 2024 · Beta-blockers (e.g., atenolol, esmolol, metoprolol, propranolol): increased risk of atrioventricular block. 3.3.4 Toxicity. No information is available for the oromucosal form. Single doses up to five times the recommended IV dose and ten times the IM dose have been tolerated in healthy young dogs (Plumb’s 2022). 3.4 Clinical Use and Dosage
