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  1. Jun 10, 2019 · Amyotrophic lateral sclerosis (ALS) is a rapidly progressive and fatal neurodegenerative disorder of the motor neurons, characterized by focal onset of muscle weakness and incessant disease progression.

  2. Feb 12, 2024 · Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a progressive, paralytic, neurodegenerative disease affecting the upper and lower motor neurons. [1] ALS is the most common motor neuron disease (MND) and has both sporadic and familial forms.

  3. Jul 7, 2020 · Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder affecting primarily the motor system, but in which extra‐motor manifestations are increasingly recognized. The loss of upper and lower motor neurons in the motor cortex, the brain stem nuclei and the anterior horn of the spinal cord gives rise to progressive muscle ...

  4. Apr 10, 2024 · Amyotrophic lateral sclerosis (a-my-o-TROE-fik LAT-ur-ul skluh-ROE-sis), known as ALS, is a nervous system disease that affects nerve cells in the brain and spinal cord. ALS causes loss of muscle control.

  5. Sep 15, 2024 · This review offers an in-depth examination of amyotrophic lateral sclerosis (ALS), addressing its epidemiology, pathophysiology, clinical presentation, diagnostic techniques, and current as well as emerging treatments.

  6. Jul 13, 2017 · Amyotrophic lateral sclerosis (ALS) is a progressive, paralytic disorder characterized by degeneration of motor neurons in the brain and spinal cord. It begins insidiously with focal weakness...

  7. Oct 5, 2017 · Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease, is characterized by the degeneration of both upper and lower motor neurons, which leads to muscle weakness and eventual...

  8. Apr 21, 2015 · Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease of the motor neurons, which results in weakness and atrophy of voluntary skeletal muscles. Treatments do not...

  9. Apr 11, 2024 · Amyotrophic lateral sclerosis (ALS) is the most common degenerative disease of the motor neuron system. The disorder is named for its underlying pathophysiology, withamyotrophy” referring to...

  10. Sep 9, 2016 · Amyotrophic lateral sclerosis (ALS) or motor neuron disease in its purest form is a readily identified clinical condition. It is a rapidly progressive degeneration of upper and lower motor neurons, which results in weakness and wasting of muscle in the arms, leg, trunk and bulbar region.