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Dec 27, 2023 · Clue cells are specialized vaginal epithelial cells that appear stippled or granulated due to being covered with numerous bacteria. Meanwhile, these cells are a critical diagnostic feature in gynecology, particularly for diagnosing bacterial vaginosis (BV), a common vaginal infection.
Clue cells are vaginal epithelial cells that have the characteristic appearance of having a grainy border (speckled appearance) when viewed under a microscope. First described by Gardner and Dukes, the presence of clue cells, along with other clinical criteria, can help diagnose bacterial vaginosis.
Jun 10, 2023 · Clue cells are vaginal cells covered in bacteria. These are a sign of BV. Test your vaginal pH. The acidity of your vagina can be tested with a pH strip. You place the test strip in your vagina. A vaginal pH of 4.5 or higher is a sign of bacterial vaginosis. More Information. Pelvic exam. Treatment.
Clue cells are epithelial cells of the vagina that get their distinctive stippled appearance by being covered with bacteria. The etymology behind the term "clue" cell derives from the original research article from Gardner and Dukes describing the characteristic cells.
May 6, 2024 · At least 3 of the 4 findings are needed to confirm the diagnosis. The Amsel criteria include a thin white to yellow, homogenous discharge, clue cells on microscopy, pH of vaginal fluid >4.5, and the release of a fishy odor after adding an alkali solution (10% KOH) to the specimen.
Clue cells are identified as vaginal epithelial cells with such a heavy coating of bacteria that the peripheral borders are obscured. If three of four criteria are met, then a clinical diagnosis of BV can be made.
Aug 16, 2023 · presence of clue cells on microscopy of a wet mount of a sample of vaginal discharge. Clinical and laboratory assessments for bacterial vaginosis can be affected by factors such as recent sexual activity, menstrual cycle, douching, and use of antimicrobial agents.
Clue cells on saline (0.9%) wet mount. Speculum Examination in Bacterial Vaginosis. Image. By permission of the publisher. From Spitzer M, Mann M.
Dec 7, 2023 · Bacterial vaginosis (BV) is a clinical condition characterized by a shift in vaginal microbiota away from Lactobacillus species toward more diverse bacterial species, including facultative anaerobes. The altered microbiome causes a rise in vaginal pH and symptoms that range from none to very bothersome (eg, abnormal vaginal discharge and odor).
Nov 10, 2022 · A clue cell can be detected on a simple wet mount of vaginal secretions. Despite receiving regular antibiotic therapy, a substantial risk of treatment failure and bacterial vaginosis recurrence persists. Researchers have revealed positive treatment effects and reduced the infection of the female reproductive system with harmful bacteria.
